Combination checkpoint inhibitor therapy induces multiple immune major related adverse events in the treatment of vaginal melanoma: A cautionary case report
Sign Up to like & getrecommendations! Published in 2019 at "Gynecologic Oncology Reports"
DOI: 10.1016/j.gore.2019.100508
Abstract: Highlights • As more ICIs are approved, better education is needed for patients and providers.• Major irAEs, signs of worsening immune toxicity, can present with benign symptoms.• IrAEs should be considered when patients on ICIs… read more here.
Keywords: inhibitor therapy; therapy induces; treatment; combination checkpoint ... See more keywords
Phase I study of recombinant interleukin-15 in combination with checkpoint inhibitors nivolumab and ipilimumab in subjects with refractory cancers.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.tps3128
Abstract: TPS3128Background: Interleukin-15 is a stimulatory cytokine. Recombinant human IL-15 (rhIL-15), a nonglycosylated single-chain peptide, increased circulating CD8+T-cells, NK cells and inflammatory ... read more here.
Keywords: study recombinant; recombinant interleukin; checkpoint inhibitors; interleukin combination ... See more keywords