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Published in 2022 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2022.114271
Abstract: A series of pyrimidine-bridged CA-4 derivatives (9a-u) targeting colchicine site were designed, synthesized and evaluated. Among them, the most potent compound 9j showed favorable anti-proliferative activities against a panel of cervical cancer cells (IC50 = 0.09-0.15 μM) and…
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Keywords:
cervical cancer;
combination cisplatin;
cancer;
pyrimidine bridged ... See more keywords
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Published in 2022 at "Drug research"
DOI: 10.1055/a-1830-8716
Abstract: Chemotherapy, which is one of the common treatments for osteosarcoma (OS), has many side effects and in some cases has low effectiveness due to chemoresistance, hence it is vital to study new therapies for OS.…
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Keywords:
increases sensitivity;
combination cisplatin;
cisplatin;
mg63 cells ... See more keywords
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2
Published in 2022 at "Journal of Dentistry"
DOI: 10.30476/dentjods.2021.89577.1478
Abstract: Statement of the Problem: Squamous cell carcinoma (SCC) comprises over 90% of oral malignancies. Cisplatin, as a selective chemotherapy agent to treat SCC, has many side effects despite its high effectiveness. There are some studies…
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Keywords:
cell;
effect;
bromelain;
combination ... See more keywords