Depigmenting topical therapy based on a synergistic combination of compounds targeting the key pathways involved in melasma pathophysiology
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DOI: 10.1111/exd.14752
Abstract: Melasma has a complex pathophysiology with different cell types and signalling pathways involved. Paracrine factors secreted by keratinocytes, fibroblasts and endothelial cells act on melanocytes and stimulate melanogenesis. These paracrine factors are involved in the… read more here.
Keywords: combination compounds; involved melasma; pathophysiology; combination ... See more keywords