Evaluation of Ceftolozane-Tazobactam in Combination with Meropenem against Pseudomonas aeruginosa Sequence Type 175 in a Hollow-Fiber Infection Model
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DOI: 10.1128/aac.00026-18
Abstract: ABSTRACT The aim of this study was to investigate the efficacy of ceftolozane-tazobactam in combination with meropenem against an extensively drug-resistant (XDR) Pseudomonas aeruginosa high-risk clone, sequence type 175, isolated in a Spanish university hospital.… read more here.
Keywords: tazobactam; combination meropenem; ceftolozane tazobactam; tazobactam combination ... See more keywords
Pharmacokinetics/Pharmacodynamics of Vaborbactam, a Novel Beta-Lactamase Inhibitor, in Combination with Meropenem
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DOI: 10.1128/aac.01659-18
Abstract: Vaborbactam is a novel beta-lactamase inhibitor with activity against important beta-lactamases, in particular, serine carbapenemases, and is currently approved in combination with meropenem as Vabomere for the treatment of complicated urinary tract infections, including pyelonephritis.… read more here.
Keywords: combination; combination meropenem; beta; vaborbactam novel ... See more keywords