Efficacy and safety of liraglutide versus sitagliptin both in combination with metformin in patients with type 2 diabetes
Sign Up to like & getrecommendations! Published in 2017 at "Medicine"
DOI: 10.1097/md.0000000000008161
Abstract: Background: The aim of this systematic review was to evaluate the efficacy and safety of liraglutide versus sitagliptin both in combination with metformin in patients with type 2 diabetes and provide reference basis for rational… read more here.
Keywords: liraglutide versus; versus sitagliptin; sitagliptin combination; metformin ... See more keywords
Phase I study of mTORC1/2 inhibitor sapanisertib (TAK-228) in combination with metformin in patients (pts) with mTOR/AKT/PI3K pathway alterations and advanced solid malignancies.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.15_suppl.3017
Abstract: 3017 Background: Sapanisertib (TAK-228) is a potent, selective ATP-competitive, dual inhibitor of mTORC1/2. Metformin is thought to inhibit the mTOR pathway through upstream activation of AMPK suggesting combination therapy may enhance anti-tumor activity of TAK-228.… read more here.
Keywords: combination; tak 228; metformin; combination metformin ... See more keywords
Supplementation with a Cocoa–Carob Blend, Alone or in Combination with Metformin, Attenuates Diabetic Cardiomyopathy, Cardiac Oxidative Stress and Inflammation in Zucker Diabetic Rats
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DOI: 10.3390/antiox11020432
Abstract: Diabetic cardiomyopathy (DCM) is one of the main causes of mortality among diabetic patients, with oxidative stress and inflammation major contributors to its development. Dietary flavonoids show strong antioxidant and anti-inflammatory activities, although their potential… read more here.
Keywords: cocoa carob; oxidative stress; stress inflammation; combination metformin ... See more keywords