Abstract 2494: ATR inhibitor AZD6738 as monotherapy and in combination with olaparib or chemotherapy: defining pre-clinical dose-schedules and efficacy modelling
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DOI: 10.1158/1538-7445.am2017-2494
Abstract: Introduction: AZD6738 is a potent and selective oral inhibitor of the ataxia telangiectasia and rad3 related (ATR) protein kinase. ATR has a key role in the DNA replication stress response (RSR) pathway of DNA repairby… read more here.
Keywords: combination; inhibitor; azd6738; pre clinical ... See more keywords