Combination of photodynamic therapy and gene silencing achieved through the hierarchical self-assembly of porphyrin-siRNA complexes.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2019.118585
Abstract: In this work, we implemented a supramolecular approach in order to combine photodynamic therapy (PDT) with gene therapy. We made use of a simple cationic guanidylated porphyrin (H2‑PG) with the hypothesis that porphyrin aggregates should… read more here.
Keywords: photodynamic therapy; therapy gene; combination photodynamic; therapy ... See more keywords
Oxidation-Responsive PolyMOF Nanoparticles for Combination Photodynamic-Immunotherapy with Enhanced STING Activation.
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DOI: 10.1021/acsnano.3c01333
Abstract: Stimulator of interferon genes (STING) activation by STING agonists has been recognized as one of the potent and promising immunotherapy strategies. However, the immunosuppressive tumor microenvironment always hinders the therapeutic efficacy of cancer immunotherapy. In… read more here.
Keywords: immunotherapy; enhanced sting; combination photodynamic; sting activation ... See more keywords
Combination of Photodynamic Therapy and Oral Antifungals for the Treatment of Onychomycosis
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15060722
Abstract: Onychomycosis accounts for 50% of nail disorders, making it one of the most prevalent fungal diseases and a therapeutic challenge. Photodynamic therapy (PDT) could constitute a therapeutic alternative, owing to its good adherence, the low… read more here.
Keywords: onychomycosis; therapy oral; combination photodynamic; photodynamic therapy ... See more keywords