Assessment of Combination Therapies vs Monotherapy for Erectile Dysfunction
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.36337
Abstract: This systematic review and meta-analysis compares the outcomes of monotherapy and combination treatments according to self-reports of erectile function by men with erectile dysfunction. read more here.
Keywords: combination; combination therapies; erectile dysfunction; assessment combination ... See more keywords
Erratum to: miRNAs: micro-managers of anticancer combination therapies
Sign Up to like & getrecommendations! Published in 2017 at "Angiogenesis"
DOI: 10.1007/s10456-017-9564-7
Abstract: In the original publication, the article was published with the copyright Springer Science?Business Media. However, it has to be published with free open access agreement. It has also been updated in the original article. read more here.
Keywords: erratum mirnas; combination therapies; mirnas micro; micro managers ... See more keywords
Efficacy and Safety of Initial Combination Therapy in Treatment-Naïve Type 2 Diabetes Patients: A Systematic Review and Meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "Diabetes Therapy"
DOI: 10.1007/s13300-018-0493-2
Abstract: IntroductionThe aim of this study was to evaluate the efficacy and safety of initial combination therapy compared with monotherapy in drug-naïve type 2 diabetes patients.MethodsMEDLINE, Embase and the Cochrane Central Register of Controlled Trials were… read more here.
Keywords: combination; combination therapies; initial combination; combination therapy ... See more keywords
Inhibition of glutaminolysis in combination with other therapies to improve cancer treatment.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in chemical biology"
DOI: 10.1016/j.cbpa.2021.01.006
Abstract: Targeting glutamine catabolism has been attracting more research attention on the development of successful cancer therapy. Catalytic enzymes such as glutaminase (GLS) in glutaminolysis, a series of biochemical reactions by which glutamine is converted to… read more here.
Keywords: combination therapies; glutaminolysis combination; inhibition glutaminolysis; cancer ... See more keywords
Independent drug action and its statistical implications for development of combination therapies.
Sign Up to like & getrecommendations! Published in 2020 at "Contemporary clinical trials"
DOI: 10.1016/j.cct.2020.106126
Abstract: Researchers have long sought to find combinations of cancer drugs that might achieve synergy. However, while observed in some preclinical tumor models, synergistic effects are rarely seen in clinical trials. In fact, growing evidence in… read more here.
Keywords: combination; combination therapies; drug action; drug ... See more keywords
A disulfide-induced supra-amphiphilic co-assembly for glycosylated pro-drug-photosensitizer nanoparticles in combination therapies.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc04777b
Abstract: A disulfide-induced supra-amphiphilic co-assembly strategy for hydrophobic drug co-delivery in combination therapies was proposed based on a disulfide bond containing hydrophobic pro-drug-photosensitizer (BG) and a hydrophilic/targeting dimer lactose molecule (Lac-SS-Lac). The anti-tumor efficiency was significantly… read more here.
Keywords: supra amphiphilic; combination therapies; induced supra; disulfide induced ... See more keywords
Emerging nanotechnology based combination therapies of taxanes for multiple drug resistant cancers.
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutical development and technology"
DOI: 10.1080/10837450.2021.2009861
Abstract: 'One drug- one target' to 'multiple drug- multiple targets' paradigm shifted to produce combination therapies, has found great outcomes to overcome multiple drug resistance (MDR). MDR is a significant barrier to the delivery of taxane… read more here.
Keywords: therapies taxanes; combination therapies; multiple drug; drug ... See more keywords
Looking ahead to potential incretin combination therapies for nonalcoholic steatohepatitis in patients with diabetes
Sign Up to like & getrecommendations! Published in 2023 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2023.2208746
Abstract: ABSTRACT Introduction There are no drugs approved by regulatory agencies for the treatment of nonalcoholic fatty liver disease (NAFLD); incretin combination therapies are being developed for treatment of type 2 diabetes and research has moved… read more here.
Keywords: combination therapies; incretin combination; combination; looking ahead ... See more keywords
The safety of DPP-4 inhibitor and SGLT2 inhibitor combination therapies
Sign Up to like & getrecommendations! Published in 2018 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2018.1497158
Abstract: ABSTRACT Introduction: Type 2 diabetes (T2D), a multifactorial and chronic disease, requires in an elevated percentage of patients the association of several antidiabetic drugs to achieve optimal glycemic control. Dipeptidyl peptidase-4 inhibitors (DPP-4i) and sodium–glucose… read more here.
Keywords: combination; inhibitor; combination therapies; safety ... See more keywords
Advances in the design of combination therapies for the treatment of tuberculosis
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2023.2157811
Abstract: ABSTRACT Introduction Tuberculosis requires lengthy multi-drug therapy. Mycobacterium tuberculosis occupies different tissue compartments during infection, making drug access and susceptibility patterns variable. Antibiotic combinations are needed to ensure each compartment of infection is reached with… read more here.
Keywords: combination therapies; tuberculosis; combination; design ... See more keywords
Latest combination therapies in psoriasis: Narrative review of the literature
Sign Up to like & getrecommendations! Published in 2022 at "Dermatologic Therapy"
DOI: 10.1111/dth.15759
Abstract: Biological therapies revolutionized the treatment of many chronic inflammatory skin diseases, first of all psoriasis, thanks to their high efficacy and the reduced number of side effects. However, the use of a single biologic drug… read more here.
Keywords: therapies psoriasis; combination therapies; combination; literature ... See more keywords