Rivaroxaban Monotherapy vs Combination Therapy With Antiplatelets on Total Thrombotic and Bleeding Events in Atrial Fibrillation With Stable Coronary Artery Disease: A Post Hoc Secondary Analysis of the AFIRE Trial.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2022.1561
Abstract: Importance Appropriate regimens of antithrombotic therapy for patients with atrial fibrillation (AF) and coronary artery disease (CAD) have not yet been established. Objective To compare the total number of thrombotic and/or bleeding events between rivaroxaban… read more here.
Keywords: rivaroxaban monotherapy; therapy; monotherapy; combination therapy ... See more keywords
Effectiveness of &bgr;-Lactam Monotherapy vs Macrolide Combination Therapy for Children Hospitalized With Pneumonia
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Pediatrics"
DOI: 10.1001/jamapediatrics.2017.3225
Abstract: Importance &bgr;-Lactam monotherapy and &bgr;-lactam plus macrolide combination therapy are both common empirical treatment strategies for children hospitalized with pneumonia, but few studies have evaluated the effectiveness of these 2 treatment approaches. Objective To compare… read more here.
Keywords: bgr lactam; combination therapy; lactam;
A Hypoxia-Activatable Prodrug for Targeted Combination Therapy of Hepatoma.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced materials"
DOI: 10.1002/adma.202412376
Abstract: Precision medicine is characterized by high accuracy and safety, showing robust superiority and significant potential in clinical applications. Organelle‐targeting therapies are important tactics for precision medicine, allowing for efficient tumor treatment and reduced off‐target toxicity.… read more here.
Keywords: combination therapy; tumor; hypoxia activatable; medicine ... See more keywords
A Combination Therapy Using Electrical Stimulation and Adaptive, Conductive Hydrogels Loaded with Self‐Assembled Nanogels Incorporating Short Interfering RNA Promotes the Repair of Diabetic Chronic Wounds
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202201425
Abstract: In addition to oxidative stress and impaired angiogenesis, the overexpression of metalloproteinases (MMPs) and proinflammatory cytokines, which are promoted by hyperglycemia, causes chronic inflammation in diabetic wounds. Herein, TA‐siRNA nanogels are prepared for the first… read more here.
Keywords: adaptive conductive; electrical stimulation; interfering rna; therapy using ... See more keywords
High-Performance Multi-Dynamic Bond Cross-Linked Hydrogel with Spatiotemporal siRNA Delivery for Gene-Cell Combination Therapy of Intervertebral Disc Degeneration.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202206306
Abstract: Chronic inflammatory diseases, such as intervertebral disc degeneration (IVDD), which affect the lives of hundreds of millions of people, still lack effective and precise treatments. In this study, a novel hydrogel system with many extraordinary… read more here.
Keywords: cell; gene cell; cell combination; sirna ... See more keywords
Tirofiban Combination Therapy for Acute Ischemic Stroke: A Systematic Review and Meta‐Analysis
Sign Up to like & getrecommendations! Published in 2025 at "Brain and Behavior"
DOI: 10.1002/brb3.70508
Abstract: Acute ischemic stroke (AIS) is a leading cause of morbidity and mortality globally. Standard antiplatelet therapies, while partially effective, do not fully inhibit all pathways of platelet aggregation, leaving patients at risk of recurrent thrombotic… read more here.
Keywords: therapy acute; acute ischemic; combination therapy; ischemic stroke ... See more keywords
Checkpoint inhibitor/interleukin‐based combination therapy of cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4659
Abstract: Immunotherapy using immune checkpoint inhibitors (ICIs) is the current focus in cancer immunotherapy. However, issues are raised in the area, as the recent studies showed that such therapeutic modality suffers from low durability and low… read more here.
Keywords: combination; checkpoint inhibitor; cancer; combination therapy ... See more keywords
Ibrutinib as monotherapy versus combination therapy in Chinese patients with relapsed/refractory mantle cell lymphoma: A multicenter study
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4765
Abstract: Ibrutinib has revolutionized the treatment of mantle cell lymphoma (MCL). Both ibrutinib monotherapy and ibrutinib‐based combination therapy are important salvage options for patients with relapsed/refractory (R/R) MCL. The real‐world efficacy and safety profile of the… read more here.
Keywords: cell lymphoma; relapsed refractory; mantle cell; ibrutinib monotherapy ... See more keywords
Durvalumab and taxane family combination therapy enhances the antitumoral effects for NSCLC: An in vitro study
Sign Up to like & getrecommendations! Published in 2024 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3919
Abstract: Immunotherapy has lately become the most preferred cancer treatment method, and for non‐small cell lung cancer (NSCLC) first‐line treatment, there are many immunotherapy options. This study aimed to assess the effectiveness and toxicity of paclitaxel… read more here.
Keywords: treatment; combination therapy; therapy; ptx dtx ... See more keywords
Real‐life effectiveness and safety of the daclatasvir/asunaprevir combination therapy for genotype 1b chronic hepatitis C patients: An emphasis on the pretreatment NS5A resistance‐associated substitution test
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25575
Abstract: This study aimed to investigate the real‐life effectiveness and safety of daclatasvir (DCV) and asunaprevir (ASV) combination therapy in Korean patients. We consecutively enrolled patients with genotype 1b hepatitis C virus (HCV) infection treated with… read more here.
Keywords: combination; life effectiveness; safety; combination therapy ... See more keywords
Design of an Injectable Polypeptide Hydrogel Depot Containing the Immune Checkpoint Blocker Anti-PD-L1 and Doxorubicin to Enhance Antitumor Combination Therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202100049
Abstract: Combination therapy can be used to enhance the therapeutic response and decrease side effects during cancer treatment. In this study, a system is developed to locally deliver the immune checkpoint blockade antibody targeting programmed death-ligand… read more here.
Keywords: immune checkpoint; combination therapy; polypeptide hydrogel; tumor ... See more keywords