CD47-SIRPα Controls ADCC Killing of Primary T Cells by PMN Through a Combination of Trogocytosis and NADPH Oxidase Activation
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DOI: 10.3389/fimmu.2022.899068
Abstract: Immunotherapies targeting the “don’t eat me” myeloid checkpoint constituted by CD47 SIRPα interaction have promising clinical potential but are limited by toxicities associated with the destruction of non-tumor cells. These dose-limiting toxicities demonstrate the need… read more here.
Keywords: combination trogocytosis; cd47 sirp; anti cd47; cd47 ... See more keywords