Articles with "combinational therapy" as a keyword



Co‐Assembled Nanoparticles toward Multi‐Target Combinational Therapy of Alzheimer's Disease by Making Full Use of Molecular Recognition and Self‐Assembly

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Published in 2024 at "Advanced Materials"

DOI: 10.1002/adma.202401918

Abstract: The complex pathologies in Alzheimer's disease (AD) severely limit the effectiveness of single‐target pharmic interventions, thus necessitating multi‐pronged therapeutic strategies. While flexibility is essentially demanded in constructing such multi‐target systems, for achieving optimal synergies and… read more here.

Keywords: alzheimer disease; multi target; target; combinational therapy ... See more keywords

Targeting Delivery of Lidocaine and Cisplatin by Nanogel Enhances Chemotherapy and Alleviates Metastasis.

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Published in 2018 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.8b09376

Abstract: Tumor growth inhibition and adverse effect reduction together with metastasis alleviation are still the challenges that need to be overcome in cancer chemotherapy. Combinational therapy provides an alternative solution for these challenges. Nanoparticles are the… read more here.

Keywords: combinational therapy; cisplatin; alleviates metastasis; lidocaine ... See more keywords

O-031 Combinational therapy following elvo in a mouse model of stroke demonstrates new frontiers in neuroprotection: the mavaric trial

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Published in 2017 at "Journal of NeuroInterventional Surgery"

DOI: 10.1136/neurintsurg-2017-snis.31

Abstract: Stroke remains a leading cause of morbidity and mortality in the United States. Potential therapies have encountered significant barriers in attempts to translate bench to bedside research. Because of this, we have evaluated novel roles… read more here.

Keywords: combinational therapy; magnesium; therapy; stroke ... See more keywords

Abstract 4072: A combinational therapy of oncolytic virus and nature killer cells for melanoma treatment

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Published in 2019 at "Immunology"

DOI: 10.1158/1538-7445.am2019-4072

Abstract: Immunotherapy has obtained substantial impact on the clinical treatment of melanoma which is largely resistant to current therapies as chemotherapy and radiotherapy. Oncolytic virotherapy of melanoma is an appealing approach for inducing not only tumor… read more here.

Keywords: combinational therapy; treatment; therapy oncolytic; melanoma ... See more keywords

The safety and efficacy of anti-PD-1 inhibitor-based combinational therapy in non-small cell lung cancer patients with oncogenic alterations

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Published in 2024 at "Translational Cancer Research"

DOI: 10.21037/tcr-23-1092

Abstract: Background The anti-programmed cell death 1 (PD-1)/programmed cell death ligand 1 (PD-L1) immunotherapy has been extensively used in patients with non-small cell lung cancer (NSCLC) in which the tumors are negative for oncogenic alterations. However,… read more here.

Keywords: therapy; anti inhibitor; inhibitor based; combinational therapy ... See more keywords

Smart Nanoparticles for Chemo-Based Combinational Therapy

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Published in 2021 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics13060853

Abstract: Cancer is a heterogeneous and complex disease. Traditional cancer therapy is associated with low therapeutic index, acquired resistance, and various adverse effects. With the increasing understanding of cancer biology and technology advancements, more strategies have… read more here.

Keywords: smart nanoparticles; combinational therapy; therapy smart; cancer ... See more keywords

Vehicle-Free Nanotheranostic Self-Assembled from Clinically Approved Dyes for Cancer Fluorescence Imaging and Photothermal/Photodynamic Combinational Therapy

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Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14051074

Abstract: Phototherapy, including photothermal therapy (PTT) and photodynamic therapy (PDT) has attracted growing attention as a noninvasive option for cancer treatment. At present, researchers have developed various “all-in-one” nanoplatforms for cancer imaging and PTT/PDT combinational therapy.… read more here.

Keywords: icg; therapy; combinational therapy; approved dyes ... See more keywords