Articles with "combinatorial approach" as a keyword



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A Combinatorial Approach for Assessing the Magnetic Properties of High Entropy Alloys: Role of Cr in AlCoxCr1–xFeNi

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Published in 2017 at "Advanced Engineering Materials"

DOI: 10.1002/adem.201700048

Abstract: A combinatorial assessment of composition-microstructure-magnetic property relationships in magnetic high entropy AlCoxCr1-xFeNi alloy (0 ≤ x ≤ 1) system has been carried out using compositionally graded alloys fabricated via laser additive manufacturing. At one end, the AlCoFeNi composition (x = 1)… read more here.

Keywords: approach assessing; combinatorial approach; high entropy; alcoxcr1 xfeni ... See more keywords
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A combinatorial approach for the discovery of drug-like inhibitors of 15-lipoxygenase-1.

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Published in 2019 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2019.04.021

Abstract: Human 15-lipoxygenase-1 (15-LOX-1) is a mammalian lipoxygenase which plays an important regulatory role in several CNS and inflammatory lung diseases. To further explore the role of this enzyme in drug discovery, novel potent inhibitors with… read more here.

Keywords: discovery drug; chemistry; drug; approach discovery ... See more keywords
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A combinatorial approach for the discovery of cytochrome P450 2D6 inhibitors from nature

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-08404-0

Abstract: The human cytochrome P450 2D6 (CYP2D6) enzyme is part of phase-I metabolism and metabolizes at least 20% of all clinically relevant drugs. Therefore, it is an important target for drug-drug interaction (DDI) studies. High-throughput screening… read more here.

Keywords: cytochrome p450; combinatorial approach; p450 2d6;
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Combinatorial approach for screening and assessment of multiple therapeutic enzymes from marine isolatePseudomonas aeruginosaAR01

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Published in 2019 at "RSC Advances"

DOI: 10.1039/c9ra02555c

Abstract: A simple and rapid screening of therapeutic enzymes from bacteria was conducted using functional- and sequence-based approach. read more here.

Keywords: assessment multiple; therapeutic enzymes; approach; combinatorial approach ... See more keywords
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An Extension of Combinatorial Contextuality for Cognitive Protocols

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Published in 2022 at "Frontiers in Psychology"

DOI: 10.3389/fpsyg.2022.871028

Abstract: This article extends the combinatorial approach to support the determination of contextuality amidst causal influences. Contextuality is an active field of study in Quantum Cognition, in systems relating to mental phenomena, such as concepts in… read more here.

Keywords: contextuality; causal; contextuality cognitive; causal influences ... See more keywords
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Optimal Design of High-Strength Ti‒Al‒V‒Zr Alloys through a Combinatorial Approach

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Published in 2018 at "Materials"

DOI: 10.3390/ma11091603

Abstract: The influence of various Zr contents (0–45 wt.%) on the microstructure and mechanical properties of Ti6Al4V alloy was investigated through a combinatorial approach. The diffusion multiples of Ti6Al4V–Ti6Al4V20Fe–Ti6Al4V20Cr–Ti6Al4V20Mo–Ti6Al4V45Zr were manufactured and diffusion-annealed to obtain a… read more here.

Keywords: strength; phase; optimal design; strength alloys ... See more keywords