Combinatorial pathway disruption is a powerful approach to delineate metabolic impacts of endocrine disruptors
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14465
Abstract: The prevalence of metabolic diseases, such as obesity, diabetes, metabolic syndrome and chronic liver diseases among others, has been rising for several years. Epidemiology and mechanistic (in vivo, in vitro and in silico) toxicology have recently provided compelling… read more here.
Keywords: combinatorial pathway; metabolic diseases; endocrine disruptors; disruption powerful ... See more keywords
Direct Combinatorial Pathway Optimization.
Sign Up to like & getrecommendations! Published in 2017 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.6b00122
Abstract: Combinatorial engineering approaches are becoming increasingly popular, yet they are hindered by the lack of specialized techniques for both efficient introduction of sequence variability and assembly of numerous DNA parts, required for the construction of… read more here.
Keywords: assembly; combinatorial pathway; pathway; biology ... See more keywords