Combinatorial Pharmacogenomic Algorithm is Predictive of Citalopram and Escitalopram Metabolism in Patients with Major Depressive Disorder
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DOI: 10.1016/j.psychres.2020.113017
Abstract: Pharmacogenomic tests used to guide clinical treatment for major depressive disorder (MDD) must be thoroughly validated. One important assessment of validity is the ability to predict medication blood levels, which reflect altered metabolism. Historically, the… read more here.
Keywords: citalopram escitalopram; blood; combinatorial pharmacogenomic; pharmacogenomic test ... See more keywords
Clinical validation of combinatorial pharmacogenomic testing and single-gene guidelines in predicting psychotropic medication blood levels and clinical outcomes in patients with depression
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DOI: 10.1016/j.psychres.2020.113649
Abstract: We evaluated the clinical validity of a combinatorial pharmacogenomic test and single-gene Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines against patient outcomes and medication blood levels to assess their ability to inform prescribing in major depressive… read more here.
Keywords: single gene; combinatorial pharmacogenomic; gene guidelines; blood levels ... See more keywords