Combinatorial Therapies After Spinal Cord Injury: How Can Biomaterials Help?
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DOI: 10.1002/adhm.201601130
Abstract: Traumatic spinal cord injury (SCI) results in an immediate loss of motor and sensory function below the injury site and is associated with a poor prognosis. The inhibitory environment that develops in response to the… read more here.
Keywords: combinatorial therapies; therapies spinal; combinatorial strategies; injury ... See more keywords
Abstract B003: Combinatorial therapies of neratinib for HER2-amplified cancer
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DOI: 10.1158/1535-7163.targ-19-b003
Abstract: Activation of HER2 signaling by amplification or overexpression of ERBB2 (HER2) is associated with the development and progression of breast cancer. Neratinib is an irreversible, pan-HER tyrosine kinase inhibitor which selectively inhibits EGFR, HER2 and… read more here.
Keywords: combinatorial therapies; cancer; her2 amplified; neratinib her2 ... See more keywords
Abstract IA12: Developing combinatorial therapies for KRAS-driven cancers
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DOI: 10.1158/1557-3125.ras23-ia12
Abstract: The RAS pathway is one of the most commonly deregulated pathways in human cancer. Approximately 30% of all tumors harbor activating mutations in either KRAS, NRAS or HRAS, and even more possess alterations in other… read more here.
Keywords: abstract ia12; combinatorial therapies; driven cancers; developing combinatorial ... See more keywords