Combined MEK and PI3K/p110b inhibition as a novel targeted therapy for malignant mesothelioma displaying sarcomatoid features.
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DOI: 10.1158/0008-5472.can-19-1633
Abstract: Among malignant mesotheliomas (MM) the sarcomatoid subtype is associated with higher chemoresistance and worst survival. Due to its low incidence, there has been little progress in the knowledge of the molecular mechanisms associated with sarcomatoid… read more here.
Keywords: pi3k; combined mek; targeted therapy; inhibition ... See more keywords