A Combined NMR and SAXS Analysis of the Partially Folded Cataract-Associated V75D γD-Crystallin.
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical journal"
DOI: 10.1016/j.bpj.2017.02.010
Abstract: A cataract is a pathological condition characterized by the clouding of the normally clear eye lens brought about by deposition of crystallin proteins in the lens fiber cells. These protein aggregates reduce visual acuity by… read more here.
Keywords: partially folded; saxs analysis; cataract; crystallin ... See more keywords
Complex of ytterbium ethylenediaminetetraacetate as combined NMR paramagnetic probe for in situ control of temperature and pH in aqueous media
Sign Up to like & getrecommendations! Published in 2018 at "Polyhedron"
DOI: 10.1016/j.poly.2017.11.007
Abstract: Abstract The paper reports variations in LIS for [Yb(H2O)n(EDTA)]− and [Yb2(EDTA)3]6− complexes as a result of variation in pD and temperature. This is the first detection of kinetically stable complexes of the yttrium subgroup with… read more here.
Keywords: aqueous media; temperature; probe; complex ytterbium ... See more keywords
New insight on the structural features of the cytotoxic auristatins MMAE and MMAF revealed by combined NMR spectroscopy and quantum chemical modelling
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-15674-1
Abstract: Antibody-drug conjugates (ADCs) are emerging as a promising class of selective drug delivery systems in the battle against cancer and other diseases. The auristatins monomethyl auristatin E (MMAE) and monomethyl auristatin F (MMAF) appear as… read more here.
Keywords: quantum chemical; chemical modelling; drug; spectroscopy ... See more keywords
Combined NMR Spectroscopy and Quantum-Chemical Calculations in Fluorescent 1,2,3-Triazole-4-carboxylic Acids Fine Structures Analysis
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24108947
Abstract: The peculiarities of the optical properties of 2-aryl-1,2,3-triazole acids and their sodium salts were investigated in different solvents (1,4-dioxane, dimethyl sulfoxide DMSO, methanol MeOH) and in mixtures with water. The results were discussed in terms… read more here.
Keywords: spectroscopy; spectroscopy quantum; chemical calculations; quantum chemical ... See more keywords