Metabolomics combined with pattern recognition and bioinformatics analysis methods for the development of pharmacodynamic biomarkers on liver fibrosis.
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DOI: 10.1039/c7mb00093f
Abstract: The major obstacle for the development of targeted therapies is the lack of pharmacodynamic (PD) biomarkers to provide an early readout of biological activities. As the modulation of metabolites may reflect the biological changes occurring… read more here.
Keywords: pharmacodynamic biomarkers; fibrosis; liver fibrosis; combined pattern ... See more keywords