Subclonal TP53 and KRAS variants combined with poor treatment response identify ultrahigh-risk pediatric patients with T-ALL
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DOI: 10.1182/bloodadvances.2024014209
Abstract: Key Points • In a case-control study, TP53/KRAS variants were enriched in relapsing patients at initial diagnosis compared with nonrelapsing patients.• In unselected patients, TP53/KRAS variants combined with poor treatment response identified a subgroup with… read more here.
Keywords: kras variants; treatment response; combined poor; variants combined ... See more keywords