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Combined Structure and Ligand-Based Design of Selective Acetylcholinesterase Inhibitors

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Published in 2021 at "Journal of chemical information and modeling"

DOI: 10.1021/acs.jcim.0c00463

Abstract: Acetylcholinesterase is a prime target for therapeutic intervention in Alzheimer's disease. Acetylcholinesterase inhibitors (AChEIs) are used to improve cognitive abilities, playing therefore an important role in disease management. Drug repurposing screening has been performed on… read more here.

Keywords: acetylcholinesterase; combined structure; acetylcholinesterase inhibitors; drug ... See more keywords