Combining ferroptosis induction with MDSC blockade renders primary tumours and metastases in liver sensitive to immune checkpoint blockade
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DOI: 10.1136/gutjnl-2022-327909
Abstract: Objective Investigating the effect of ferroptosis in the tumour microenvironment to identify combinatory therapy for liver cancer treatment. Design Glutathione peroxidase 4 (GPx4), which is considered the master regulator of ferroptosis, was genetically altered in… read more here.
Keywords: ferroptosis induction; combining ferroptosis; blockade; ferroptosis ... See more keywords