Understanding intratumor heterogeneity by combining genome analysis and mathematical modeling
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DOI: 10.1111/cas.13510
Abstract: Cancer is composed of multiple cell populations with different genomes. This phenomenon called intratumor heterogeneity (ITH) is supposed to be a fundamental cause of therapeutic failure. Therefore, its principle‐level understanding is a clinically important issue.… read more here.
Keywords: intratumor heterogeneity; mathematical modeling; genome analysis; analysis mathematical ... See more keywords