Combining inhibition of immune checkpoints and PARP: rationale and perspectives in cancer treatment
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Therapeutic Targets"
DOI: 10.1080/14728222.2022.2158813
Abstract: ABSTRACT Introduction Genomic instability resulting from the inability of cells to repair DNA damage is a breeding ground for immune checkpoint inhibitors (ICIs) and targeted treatments. Poly (ADP-ribose) polymerase inhibitors (PARPi) interfere with the efficient… read more here.
Keywords: inhibition immune; damage; dna damage; combination ... See more keywords