Combining metformin with lactate transport inhibitors as a treatment modality for cancer - recommendation proposal
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DOI: 10.3389/fonc.2022.1034397
Abstract: Highly glycolytic cancer cells excrete lactate to maintain cellular homeostasis. Inhibiting lactate export by pharmacological targeting of plasma membrane lactate transporters is being pursued as an anti-cancer therapy. Work from many laboratories show that the… read more here.
Keywords: lactate transport; transport inhibitors; cancer; combining metformin ... See more keywords