Combining molecular dynamics simulations and experimental analyses in protein misfolding.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in protein chemistry and structural biology"
DOI: 10.1016/bs.apcsb.2019.10.001
Abstract: The fold of a protein determines its function and its misfolding can result in loss-of-function defects. In addition, for certain proteins their misfolding can lead to gain-of-function toxicities resulting in protein misfolding diseases such as… read more here.
Keywords: protein misfolding; molecular dynamics; experimental analyses; combining molecular ... See more keywords
Combining molecular and immunohistochemical analyses of key drivers in primary melanomas: interplay between germline and somatic variations
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.23204
Abstract: Due to the high mutational somatic burden of Cutaneous Malignant Melanoma (CMM) a thorough profiling of the driver mutations and their interplay is necessary to explain the timing of tumorigenesis or for the identification of… read more here.
Keywords: interplay germline; key drivers; combining molecular; germline somatic ... See more keywords