Combined therapies to treat complex diseases: The role of the gut microbiota in multiple sclerosis.
Sign Up to like & getrecommendations! Published in 2018 at "Autoimmunity reviews"
DOI: 10.1016/j.autrev.2017.11.019
Abstract: The commensal microbiota has emerged as an environmental risk factor for multiple sclerosis (MS). Studies in experimental autoimmune encephalomyelitis (EAE) models have shown that the commensal microbiota is an essential player in triggering autoimmune demyelination.… read more here.
Keywords: gut; microbiota; environmental risk; commensal microbiota ... See more keywords
Commensal microbiota-derived metabolite agmatine triggers inflammation to promote colorectal tumorigenesis
Sign Up to like & getrecommendations! Published in 2024 at "Gut Microbes"
DOI: 10.1080/19490976.2024.2348441
Abstract: ABSTRACT Colorectal cancer (CRC), a malignant tumor worldwide, is associated with gut microbiota. The influence of gut microbe-derived metabolites on CRC has attracted a lot of attention. However, the role of immunity mediated by commensal… read more here.
Keywords: derived metabolite; commensal microbiota; crc; agmatine ... See more keywords
Inference of the Demographic Histories and Selective Effects of Human Gut Commensal Microbiota Over the Course of Human History
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msaf010
Abstract: Abstract Despite the importance of gut commensal microbiota to human health, there is little knowledge about their evolutionary histories, including their demographic histories and distributions of fitness effects (DFEs) of mutations. Here, we infer the… read more here.
Keywords: commensal microbiota; gut commensal; history; demographic histories ... See more keywords
The Effects of Sleep on the Commensal Microbiota: Eyes Wide Open?
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Gastroenterology"
DOI: 10.1097/mcg.0000000000000965
Abstract: Sleep dysfunction is an epidemic, the implications of which have a profound impact on a variety of gastrointestinal disease. Recent data suggests a relationship between sleep dysfunction and intestinal dysbiosis, a known proinflammatory driver. This… read more here.
Keywords: commensal; effects sleep; sleep dysfunction; commensal microbiota ... See more keywords
Food antigens drive spontaneous IgE elevation in the absence of commensal microbiota
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aaw1507
Abstract: Food antigens drive spontaneous IgE elevation in the absence of microbiota by inducing IL-4–producing T follicular helper cells. Immunoglobulin E (IgE), a key mediator in allergic diseases, is spontaneously elevated in mice with disrupted commensal… read more here.
Keywords: antigens drive; food antigens; commensal microbiota; ige elevation ... See more keywords
Influence of Commensal Microbiota on the Enteric Nervous System and Its Role in Neurodegenerative Diseases
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Innate Immunity"
DOI: 10.1159/000488629
Abstract: When thinking about neurodegenerative diseases, the first symptoms that come to mind are loss of memory and learning capabilities, which all resemble hallmarks of manifestation of such diseases in the central nervous system (CNS). However,… read more here.
Keywords: system; nervous system; influence commensal; neurodegenerative diseases ... See more keywords
Norovirus interactions with the commensal microbiota
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1007183
Abstract: Human norovirus (HNoV) is the leading cause of epidemic nonbacterial gastroenteritis worldwide, causing an acute diarrheal infection and occasionally chronic infection in immunocompromised individuals. Mouse and tissue culture models utilizing murine norovirus (MNoV) have allowed… read more here.
Keywords: infection; commensal microbiota; mnov infection; interactions commensal ... See more keywords
Complement C3 deficient mice show more severe imiquimod-induced psoriasiform dermatitis than wild-type mice regardless of the commensal microbiota
Sign Up to like & getrecommendations! Published in 2024 at "Experimental Animals"
DOI: 10.1538/expanim.24-0043
Abstract: The complement active product, C3a, and the receptor C3aR comprise an axis that exerts various biological functions, such as protection against infection. C3a is highly expressed in the inflamed skin and blood from patients with… read more here.
Keywords: mice; dermatitis; commensal microbiota; psoriasiform dermatitis ... See more keywords
Editorial: Mechanism of colonization and persistence of gut commensal microbiota and pathogens
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2023.1176453
Abstract: COPYRIGHT © 2023 Castro-Córdova, Pizarro-Guajardo and Romero-Rodrı́guez. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided… read more here.
Keywords: commensal microbiota; editorial mechanism; persistence gut; colonization persistence ... See more keywords
IgA in human health and diseases: Potential regulator of commensal microbiota
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1024330
Abstract: Gut microbiota has extensive and tremendous impacts on human physiology and pathology. The regulation of microbiota is therefore a cardinal problem for the mutualistic relationship, as both microbial overgrowth and excessive immune reactions toward them… read more here.
Keywords: commensal microbiota; microbiota; gut microbiota; human health ... See more keywords
Conjunctival Intraepithelial Lymphocytes, Lacrimal Cytokines and Ocular Commensal Microbiota: Analysis of the Three Main Players in Allergic Conjunctivitis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.911022
Abstract: Conjunctival intraepithelial lymphocytes, tear soluble molecules and commensal microbiota have important roles in the ocular mucosal immune response in healthy and diseased subjects. For the purpose of this study, the cellular and microbial populations of… read more here.
Keywords: commensal microbiota; allergic conjunctivitis; conjunctivitis; perennial allergic ... See more keywords