Common lines modeling for reference free Ab-initio reconstruction in cryo-EM.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of structural biology"
DOI: 10.1016/j.jsb.2017.09.007
Abstract: We consider the problem of estimating an unbiased and reference-free ab initio model for non-symmetric molecules from images generated by single-particle cryo-electron microscopy. The proposed algorithm finds the globally optimal assignment of orientations that simultaneously… read more here.
Keywords: reference free; model; free initio; common lines ... See more keywords
A kinetic model for solving a combination optimization problem in ab-initio Cryo-EM 3D reconstruction
Sign Up to like & getrecommendations! Published in 2024 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbad473
Abstract: Abstract Cryo-Electron Microscopy (cryo-EM) is a widely used and effective method for determining the three-dimensional (3D) structure of biological molecules. For ab-initio Cryo-EM 3D reconstruction using single particle analysis (SPA), estimating the projection direction of… read more here.
Keywords: projection; problem; cryo; reconstruction ... See more keywords