Translating molecular advances in Down syndrome and Fragile X syndrome into therapies
Sign Up to like & getrecommendations! Published in 2018 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2018.03.006
Abstract: Ongoing treatments for genetic developmental disorders of the central nervous system are mostly symptomatic and do not correct the genetic cause. Recent identification of common mechanisms between diseases has suggested that new therapeutic targets could… read more here.
Keywords: advances syndrome; common mechanisms; fragile syndrome; molecular advances ... See more keywords
Common mechanisms for type 2 diabetes and psychosis: Findings from a prospective birth cohort
Sign Up to like & getrecommendations! Published in 2020 at "Schizophrenia Research"
DOI: 10.1016/j.schres.2020.08.006
Abstract: Background Psychosis and type 2 diabetes mellitus (T2DM) are commonly comorbid and may share pathophysiologic mechanisms. To investigate shared genetic variation and inflammation as potential common mechanisms, we tested: (i) associations between genetic predisposition for… read more here.
Keywords: t2dm; common mechanisms; inflammation; type diabetes ... See more keywords
Common Mechanisms of Viral Injury to the Kidney.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in chronic kidney disease"
DOI: 10.1053/j.ackd.2018.12.002
Abstract: Viral infections in an immunocompetent host can cause both acute and chronic kidney diseases, either by direct damage to the infected kidney cells or as a consequence of systemic immune responses that impact the kidneys'… read more here.
Keywords: medicine; common mechanisms; kidney diseases; immune responses ... See more keywords
Potential Common Mechanisms of Cytotoxicity Induced by Amide Herbicides via TRPA1 Channel Activation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph19137985
Abstract: The “Multi-Threat Medical Countermeasure (MTMC)” strategy was proposed to develop a single drug with therapeutic efficacy against multiple pathologies or broad-spectrum protection against various toxins with common biochemical signals, molecular mediators, or cellular processes. This… read more here.
Keywords: cytotoxicity; amide herbicides; mechanisms cytotoxicity; common mechanisms ... See more keywords