A Common Molecular Switch for H2S to Regulate Multiple Protein Targets.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-16-0991-6_1
Abstract: Hydrogen sulfide, a small molecule, produced by endogenous enzymes, such as CTH, CBS, and MPST using L-cysteine as substrates, has been reported to have numerous protective effects. However, the key problem that the target of… read more here.
Keywords: common molecular; protein targets; switch h2s; molecular switch ... See more keywords
Allicin pharmacology: Common molecular mechanisms against neuroinflammation and cardiovascular diseases.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117513
Abstract: According to investigations in phytomedicine and ethnopharmacology, the therapeutic properties of garlic (Allium sativum) have been described by ancestral cultures. Notwithstanding, it is of particular concern to elucidate the molecular mechanisms underlying this millenary empirical… read more here.
Keywords: common molecular; cardiovascular diseases; pharmacology; allicin pharmacology ... See more keywords
Integrative Analyses of Transcriptomes to Explore Common Molecular Effects of Antipsychotic Drugs
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23147508
Abstract: There is little understanding of the underlying molecular mechanism(s) involved in the clinical efficacy of antipsychotics for schizophrenia. This study integrated schizophrenia-associated transcriptional perturbations with antipsychotic-induced gene expression profiles to detect potentially relevant therapeutic targets… read more here.
Keywords: antipsychotic drugs; explore common; analyses transcriptomes; integrative analyses ... See more keywords