Association of a Common NOS1AP Variant with Attenuation of QTc Prolongation in Men with Heroin Dependence Undergoing Methadone Treatment
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DOI: 10.3390/jpm12050835
Abstract: Background: The effects of methadone-induced severe prolongation of the corrected QT interval (QTc) and sudden cardiac death appear unpredictable and sex-dependent. Genetic polymorphisms in the nitric oxide synthase 1 adaptor protein (NOS1AP) have been implicated… read more here.
Keywords: prolongation; common nos1ap; qtc prolongation; methadone treatment ... See more keywords