Potential Common Pathogenic Pathways for the Left Ventricular Noncompaction Cardiomyopathy (LVNC)
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Cardiology"
DOI: 10.1007/s00246-018-1882-z
Abstract: Ventricular trabeculation and compaction are two essential morphogenetic events for generating a functionally competent ventricular wall. A significant reduction in trabeculation is usually associated with hypoplastic wall and ventricular compact zone deficiencies, which commonly leads… read more here.
Keywords: noncompaction; cardiomyopathy; common pathogenic; ventricular noncompaction ... See more keywords
Common Pathogenic Mechanisms in Centronuclear and Myotubular Myopathies and Latest Treatment Advances
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DOI: 10.3390/ijms222111377
Abstract: Centronuclear myopathies (CNM) are rare congenital disorders characterized by muscle weakness and structural defects including fiber hypotrophy and organelle mispositioning. The main CNM forms are caused by mutations in: the MTM1 gene encoding the phosphoinositide… read more here.
Keywords: gene encoding; mechanisms centronuclear; pathogenic mechanisms; cnm ... See more keywords