Simultaneous dual AV node antegrade conduction (2 for 1) and lower common pathway (2–1) block illustrate AVNRT physiology
Sign Up to like & getrecommendations! Published in 2019 at "Indian Pacing and Electrophysiology Journal"
DOI: 10.1016/j.ipej.2019.12.007
Abstract: We report a rare case of spontaneous initiation of Atrioventricular nodal reentry tachycardia (AVNRT) via 2 for 1 phenomenon, into a 2:1 AV block due to lower common pathway block and finally transition to 1:1… read more here.
Keywords: avnrt; block; lower common; physiology ... See more keywords
Genome editing of factor X in zebrafish reveals unexpected tolerance of severe defects in the common pathway.
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood-2017-02-765206
Abstract: Deficiency of factor X (F10) in humans is a rare bleeding disorder with a heterogeneous phenotype and limited therapeutic options. Targeted disruption of F10 and other common pathway factors in mice results in embryonic/neonatal lethality… read more here.
Keywords: genome editing; editing factor; f10; common pathway ... See more keywords
Inflammation: The Common Pathway of Stress-Related Diseases
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Human Neuroscience"
DOI: 10.3389/fnhum.2017.00316
Abstract: While modernization has dramatically increased lifespan, it has also witnessed that the nature of stress has changed dramatically. Chronic stress result failures of homeostasis thus lead to various diseases such as atherosclerosis, non-alcoholic fatty liver… read more here.
Keywords: stress related; related diseases; inflammation; stress ... See more keywords
Endoglin Is an Important Mediator in the Final Common Pathway of Chronic Kidney Disease to End-Stage Renal Disease
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010646
Abstract: Chronic kidney disease (CKD) is a slow-developing, progressive deterioration of renal function. The final common pathway in the pathophysiology of CKD involves glomerular sclerosis, tubular atrophy and interstitial fibrosis. Transforming growth factor-beta (TGF-β) stimulates the… read more here.
Keywords: endoglin; disease; kidney; final common ... See more keywords