Patient-Centered Pain Care Using Artificial Intelligence and Mobile Health Tools: A Randomized Comparative Effectiveness Trial.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2022.3178
Abstract: Importance Cognitive behavioral therapy for chronic pain (CBT-CP) is a safe and effective alternative to opioid analgesics. Because CBT-CP requires multiple sessions and therapists are scarce, many patients have limited access or fail to complete… read more here.
Keywords: cbt; effectiveness trial; artificial intelligence; pain ... See more keywords
Comparative Effectiveness of Behavioral Interventions on Quality of Life for Older Adults With Mild Cognitive Impairment
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2019.3016
Abstract: This cluster randomized, multicomponent comparative effectiveness trial compares the incremental effects of combinations of 5 behavioral interventions on outcomes of highest importance to patients with mild cognitive impairment. read more here.
Keywords: effectiveness behavioral; cognitive impairment; behavioral interventions; comparative effectiveness ... See more keywords
Comparative Effectiveness Associated With Buprenorphine and Naltrexone in Opioid Use Disorder and Cooccurring Polysubstance Use
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.11363
Abstract: Key Points Question What is the prevalence and comparative effectiveness associated with buprenorphine and naltrexone in individuals with opioid use disorder (OUD) and cooccurring substance use disorders (SUDs)? Findings This comparative effectiveness study evaluated 179 280… read more here.
Keywords: buprenorphine; effectiveness associated; use; comparative effectiveness ... See more keywords
Comparative Effectiveness of Empagliflozin vs Liraglutide or Sitagliptin in Older Adults With Diverse Patient Characteristics
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.37606
Abstract: Key Points Question What is the comparative risk of cardiovascular outcomes associated with empagliflozin vs liraglutide or sitagliptin, overall and across strata of age, sex, baseline atherosclerotic cardiovascular diseases, heart failure, and chronic kidney disease?… read more here.
Keywords: liraglutide sitagliptin; empagliflozin liraglutide; older adults; risk ... See more keywords
Comparative Effectiveness of Immune Checkpoint Inhibitors vs Chemotherapy in Patients With Metastatic Colorectal Cancer With Measures of Microsatellite Instability, Mismatch Repair, or Tumor Mutational Burden
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.52244
Abstract: This comparative effectiveness research study compares outcomes of first-line therapy with immune checkpoint inhibitors vs chemotherapy among patients who have metastatic colorectal cancer with high microsatellite instability, mismatch repair deficiency, and/or high tumor mutational burden. read more here.
Keywords: checkpoint inhibitors; immune checkpoint; metastatic colorectal; inhibitors chemotherapy ... See more keywords
Comparative Effectiveness of 2 Interventions to Increase Breast, Cervical, and Colorectal Cancer Screening Among Women in the Rural US
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.11004
Abstract: Key Points Question What is the comparative effectiveness of 2 tailored interventions delivered remotely compared with usual care for increasing any or all needed cancer screenings in rural women? Findings In this randomized clinical trial… read more here.
Keywords: effectiveness interventions; increase breast; interventions increase; comparative effectiveness ... See more keywords
Comparative Effectiveness of Cladribine and S1P Receptor Modulators in Treatment-Naive Relapsing-Remitting MS
Sign Up to like & getrecommendations! Published in 2025 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2025.41025
Abstract: Key Points Question How does cladribine compare with sphingosine-1-phosphate receptor modulators (S1PRMs) in treatment-naive patients with relapsing-remitting multiple sclerosis? Findings In this comparative effectiveness research study of 950 propensity score–matched treatment-naive patients with at least… read more here.
Keywords: treatment; cladribine; relapsing remitting; comparative effectiveness ... See more keywords
ISPE-endorsed guidance in using electronic health records for comparative effectiveness research in COVID-19: opportunities and trade-offs.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical pharmacology and therapeutics"
DOI: 10.1002/cpt.2560
Abstract: As the scientific research community along with health care professionals and decision-makers around the world fight tirelessly against the COVID-19 pandemic, the need for comparative effectiveness research (CER) on preventive and therapeutic interventions for COVID-19… read more here.
Keywords: comparative effectiveness; electronic health; health; covid ... See more keywords
Comparative Effectiveness of Ticagrelor, Prasugrel, and Clopidogrel for Secondary Prophylaxis in Acute Coronary Syndrome: A Propensity Score‐Matched Cohort Study
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.2797
Abstract: Comparative effectiveness evaluation of newer P2Y12 inhibitors (prasugrel and ticagrelor) compared with clopidogrel after acute coronary syndrome (ACS) is limited in real‐world US populations. The objective of this study was to evaluate cardiovascular events based… read more here.
Keywords: ticagrelor; prasugrel clopidogrel; clopidogrel; comparative effectiveness ... See more keywords
Comparative Effectiveness of First‐Line Pembrolizumab vs. Chemotherapy in aNSCLC: A Norwegian Population‐Based Cohort Study
Sign Up to like & getrecommendations! Published in 2024 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.3591
Abstract: The KEYNOTE‐0421,2 trial showed the benefit of treating patients with non‐oncogene addicted advanced NSCLC with PD‐L1 tumor proportion score over 50% with pembrolizumab as monotherapy over platinum‐doublet chemotherapy. To contextualize these results, we undertake a… read more here.
Keywords: pembrolizumab; chemotherapy; population; comparative effectiveness ... See more keywords
Real‐world comparative effectiveness and safety of Pertuzumab in patients with HER2+ metastatic breast cancer: A pan‐Canadian population‐based cohort study
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Cancer"
DOI: 10.1002/ijc.35448
Abstract: We assessed the comparative effectiveness and safety of pertuzumab plus trastuzumab and chemotherapy versus trastuzumab and chemotherapy for patients with HER2+ metastatic breast cancer (mBC) in Canada. We conducted a population‐based retrospective study of patients… read more here.
Keywords: effectiveness safety; cancer; treatment; safety pertuzumab ... See more keywords