Comparative functional genomics of the acarbose producers reveals potential targets for metabolic engineering
Sign Up to like & getrecommendations! Published in 2019 at "Synthetic and Systems Biotechnology"
DOI: 10.1016/j.synbio.2019.01.001
Abstract: The α-glucosidase inhibitor acarbose is produced in large-scale by strains derived from Actinoplanes sp. SE50 and used widely for the treatment of type-2 diabetes. Compared with the wild-type SE50, a high-yield derivative Actinoplanes sp. SE50/110… read more here.
Keywords: engineering; acarbose yield; acb cluster; yield ... See more keywords
Comparative functional responses of native and high‐impacting invasive fishes: impact predictions for native prey populations
Sign Up to like & getrecommendations! Published in 2017 at "Ecology of Freshwater Fish"
DOI: 10.1111/eff.12297
Abstract: Comparative functional responses (FRs) can predict impacts of invasive species,including piscivorous fishes, via quantifying their depletion of native food resources as a function of prey density. The utility of FRs for predicting impacts on prey… read more here.
Keywords: invasive fishes; native fishes; comparative functional; functional responses ... See more keywords
Comparative functional genomics identifies unique molecular features of EPSCs
Sign Up to like & getrecommendations! Published in 2022 at "Life Science Alliance"
DOI: 10.26508/lsa.202201608
Abstract: The authors provide a comprehensive resource on proteomics, transcriptomic, and epigenetic level details of EPSCs to shed light on possible molecular pathways regulating their expanded pluripotency potential. Extended pluripotent or expanded potential stem cells (EPSCs)… read more here.
Keywords: comparative functional; identifies unique; genomics identifies; functional genomics ... See more keywords