The first biosimilar approved for the treatment of osteoporosis: results of a comparative pharmacokinetic/pharmacodynamic study
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DOI: 10.1007/s00198-018-4741-0
Abstract: SummaryTo demonstrate the clinical comparability between RGB-10 (a biosimilar teriparatide) and the originator, a comparative pharmacokinetic trial was conducted. The study was successful in establishing bioequivalence. Marketing authorisation for RGB-10 (Terrosa®) was granted by the… read more here.
Keywords: comparative pharmacokinetic; study; biosimilar approved; pharmacokinetic pharmacodynamic ... See more keywords
Comparative Pharmacokinetic Study of Two Pyrrolizidine Alkaloids Lasiocarpine and Heliotrine in Rats
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DOI: 10.1055/a-1915-5456
Abstract: Abstract Lasiocarpine (LAS) and heliotrine (HEL) are two different ester types of toxic pyrrolizidine alkaloids (PAs): open-chain diester and monoester. However, the pharmacokinetics of these two types of PAs in rats have not been reported.… read more here.
Keywords: pharmacokinetic study; study two; comparative pharmacokinetic; pyrrolizidine alkaloids ... See more keywords