Comparative Photoaffinity Profiling of Omega-3 Signaling Lipid Probes Reveals Prostaglandin Reductase 1 as a Metabolic Hub in Human Macrophages
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DOI: 10.1021/jacs.2c06827
Abstract: The fish oil constituent docosahexaenoic acid (DHA, 22:6 n-3) is a signaling lipid with anti-inflammatory properties. The molecular mechanisms underlying the biological effect of DHA are poorly understood. Here, we report the design, synthesis, and… read more here.
Keywords: omega signaling; human macrophages; comparative photoaffinity; signaling lipid ... See more keywords