Comparative structural and evolutionary analyses predict functional sites in the artemisinin resistance malaria protein K13
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DOI: 10.1038/s41598-019-47034-6
Abstract: Numerous mutations in the Plasmodium falciparum Kelch13 (K13) protein confer resistance to artemisinin derivatives, the current front-line antimalarial drugs. K13 is an essential protein that contains BTB and Kelch-repeat propeller (KREP) domains usually found in… read more here.
Keywords: protein; comparative structural; k13; artemisinin resistance ... See more keywords
Comparative structural analyses of the NHL domains from the human E3 ligase TRIM–NHL family
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DOI: 10.1107/s2052252522008582
Abstract: Family-wide structural analyses of human TRIM NHL domains reveal evolutionary divergence of their β-propeller architecture that might be essential for recruiting diverse interacting partners and for the roles of NHL domains as E3 ligases. read more here.
Keywords: analyses nhl; structural analyses; family; trim nhl ... See more keywords
Comparative structural analysis on the mitochondrial DNAs from various strains of Lentinula edodes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1034387
Abstract: The evolution of mitochondria through variations in mitochondrial DNA (mtDNA) is one of the intriguing questions in eukaryotic cells. In order to assess the causes of the variations in mitochondria, the mtDNAs of the 21… read more here.
Keywords: repeated sequences; strains lentinula; structural analysis; size ... See more keywords