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   Articles with "compared placebo" as a keyword



Coagulant Effect and Tolerability of Yeast-Produced Recombinant Batroxobin in Healthy Adult Subjects

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recommendations! Published in 2018 at "Clinical Drug Investigation"

DOI: 10.1007/s40261-018-0673-x

Abstract: Background and ObjectiveBatroxobin, a snake venom thrombin-like enzyme, converts fibrinogen into fibrin by cleaving fibrinopeptide A. It is used for hemostasis; however, the supply of native batroxobin is limited. Therefore, we developed a recombinant batroxobin… read more here.

Keywords: recombinant batroxobin; group; study; compared placebo ... See more keywords
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Safety and Efficacy of Ubrogepant for the Acute Treatment of Episodic Migraine: A Meta-Analysis of Randomized Clinical Trials

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recommendations! Published in 2020 at "CNS Drugs"

DOI: 10.1007/s40263-020-00715-7

Abstract: Background Ubrogepant is a small molecular calcitonin gene–related peptide receptor antagonist that is used for the acute treatment of migraine. Objective The aim was to conduct a meta-analysis to systematically evaluate the efficacy and safety… read more here.

Keywords: episodic migraine; migraine; treatment; randomized clinical ... See more keywords

Evaluation of Individual Items of the Patient Health Questionnaire (PHQ-9) and Montgomery-Asberg Depression Rating Scale (MADRS) in Adults with Treatment-Resistant Depression Treated with Esketamine Nasal Spray Combined with a New Oral Antidepressant

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recommendations! Published in 2022 at "CNS Drugs"

DOI: 10.1007/s40263-022-00916-2

Abstract: The objective of this study was to determine which symptoms measured by the Patient Health Questionnaire (PHQ-9) and Montgomery-Asberg Depression Rating Scale (MADRS) improve in those treated with esketamine nasal spray in combination with oral… read more here.

Keywords: placebo plus; treated esketamine; phq; esketamine plus ... See more keywords

Atorvastatin Versus Placebo for Prostate Cancer Before Radical Prostatectomy-A Randomized, Double-blind, Placebo-controlled Clinical Trial.

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recommendations! Published in 2018 at "European urology"

DOI: 10.1016/j.eururo.2018.06.037

Abstract: We tested whether intervention with atorvastatin affects the prostate beneficially compared with placebo in men with prostate cancer in a randomized clinical trial. A total of 160 statin-naïve prostate cancer patients scheduled for radical prostatectomy… read more here.

Keywords: placebo; compared placebo; atorvastatin; prostate cancer ... See more keywords

A systematic review and network meta-analysis comparing treatments for faecal incontinence.

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recommendations! Published in 2019 at "International journal of surgery"

DOI: 10.1016/j.ijsu.2019.04.007

Abstract: BACKGROUND Although numerous treatments exist for fecal incontinence (FI), no consensus exists on the best treatment strategy. The aim was to review the literature and to compare the clinical outcomes and effectiveness of treatments available… read more here.

Keywords: faecal incontinence; comparing treatments; incontinence; compared placebo ... See more keywords

Mediators of youth anxiety outcomes 3 to 12 years after treatment.

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recommendations! Published in 2020 at "Journal of anxiety disorders"

DOI: 10.1016/j.janxdis.2020.102188

Abstract: OBJECTIVE Test changes in perceived coping efficacy, negative self-statements, and interpretive biases to threat during treatment as potential mediators of the relationship between randomly assigned treatment conditions and long-term anxiety follow-ups. Age at randomization was… read more here.

Keywords: intervention; anxiety; treatment; anxiety outcomes ... See more keywords

Omega-3-polyunsatured fatty acids (O3PUFAs), compared to placebo, reduced symptoms of occupational burnout and lowered morning cortisol secretion

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recommendations! Published in 2019 at "Psychoneuroendocrinology"

DOI: 10.1016/j.psyneuen.2019.104384

Abstract: BACKGROUND Occupational burnout is both a serious health concern at both public and individual levels. Treatment options are psychopharmacological, psychological and physical activity-related interventions. Here, we tested whether, compared to placebo, omega-3-polyunsaturated fatty acids (O3PUFAs)… read more here.

Keywords: fatty acids; compared placebo; morning; placebo ... See more keywords

Morphine compared to placebo for procedural pain in preterm infants: safety, efficacy and equipoise

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recommendations! Published in 2019 at "Journal of Perinatology"

DOI: 10.1038/s41372-019-0476-9

Abstract: Among nonventilated preterm infants, who are less than 32 weeks of gestation or with birth weight less than 1501 g, undergoing an eye examination to detect retinopathy of prematurity (ROP) or heel lancing, will a… read more here.

Keywords: morphine compared; efficacy; compared placebo; preterm infants ... See more keywords

Efficacy and safety of GLP-1 agonists in the treatment of T2DM: A systematic review and network meta-analysis

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-09807-0

Abstract: To compare efficacy and safety of glucagon-like peptide-1 receptor agonists (GLP-1RAs) in subjects with type 2 diabetes (T2DM). Electronic databases were searched from inception to 2nd October 2024 for randomised controlled trials comparing GLP-1RAs treating… read more here.

Keywords: glp; compared placebo; network meta; safety ... See more keywords

Aprocitentan: a new emerging prospect in the pharmacotherapy of hypertension

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recommendations! Published in 2024 at "Blood Pressure"

DOI: 10.1080/08037051.2024.2424824

Abstract: Abstract Background Resistant hypertension (RH) is linked to higher risks of cardiovascular events and there remains an unmet therapeutic need driven by pathophysiologic pathways unaddressed by guideline-recommended therapy. Whilst spironolactone is considered the preferred fourth-line… read more here.

Keywords: pharmacotherapy; drug; profile; compared placebo ... See more keywords

Assessment of Urolithin A effects on muscle endurance, strength, inflammation, oxidative stress, and protein metabolism in male athletes with resistance training: an 8-week randomized, double-blind, placebo-controlled study

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recommendations! Published in 2024 at "Journal of the International Society of Sports Nutrition"

DOI: 10.1080/15502783.2024.2419388

Abstract: ABSTRACT Background This study aimed to investigate the impact of Urolithin A (UA) on muscle endurance, muscle strength, inflammatory levels, oxidative stress, and protein metabolism status in resistance-trained male athletes. Method An 8-week randomized, double-blind,… read more here.

Keywords: muscle; oxidative stress; group; placebo ... See more keywords