Comparison of oligosaccharide labeling employing reductive amination and hydrazone formation chemistries
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DOI: 10.1002/elps.201900475
Abstract: In this work, we compare labeling by two negatively charged fluorescent labels, 8‐aminopyrene‐1,3,6‐trisulfonic acid (APTS) and 8‐(2‐hydrazino‐2‐oxoethoxy)pyrene‐1,3,6‐trisulfonic acid (Cascade Blue hydrazide [CBH]). Effectiveness of the labeling chemistries were investigated by 4‐hydroxybenzaldehyde and maltoheptaose followed by… read more here.
Keywords: hydrazone formation; reductive amination; comparison oligosaccharide;