Exploring Multi-Compartment Plug-Flow Based Model Approach in Biopharmaceutics: Impact of Stomach Setting and the Estimation of the Fraction Absorbed of Orally Administered Basic Drugs.
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DOI: 10.1016/j.xphs.2019.11.021
Abstract: There has been an increasing interest in accurate prediction of human pharmacokinetics (PK) of drug candidates in order to reduce cost and increase productivity during research and development. Modeling efforts have primarily focused on predicting… read more here.
Keywords: compartment plug; multi compartment; basic drugs; compartment ... See more keywords