Dopamine compartmentalization, selective dopaminergic vulnerabilities in Parkinson's disease and therapeutic opportunities
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.707
Abstract: Progressive depletion of selected dopamine neurons is central to much Parkinson's disease (PD) disability. Although symptomatic treatments can ameliorate the disabilities that this neuronal depletion causes, no current strategy is documented to slow these losses.… read more here.
Keywords: selective dopaminergic; compartmentalization; compartmentalization selective; parkinson disease ... See more keywords
Compartmentalization of hepatitis C virus variants in patients with hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22500
Abstract: Chronic Hepatitis C Virus (HCV) infection is a major risk for hepatocellular carcinoma (HCC) development. HCV Core protein has been associated with the modulation of potentially oncogenic cellular processes and E2 protein has been useful… read more here.
Keywords: hepatocellular carcinoma; compartmentalization; hcv; hepatitis virus ... See more keywords
Bacteria‐Inspired Aqueous‐in‐Aqueous Compartmentalization by In Situ Interfacial Biomineralization
Sign Up to like & getrecommendations! Published in 2022 at "Small Methods"
DOI: 10.1002/smtd.202201309
Abstract: Compartmentalization is essential for living cells to orchestrate their biological processes with controlled external influences. Thus, compartmentalization has been a constant theme for cell‐mimicking materials. Despite recent advances in engineering compartmentalized materials as synthetic cells… read more here.
Keywords: aqueous aqueous; situ; compartmentalization; compartmentalized materials ... See more keywords
Evidence for altered dendritic spine compartmentalization in Alzheimer’s disease and functional effects in a mouse model
Sign Up to like & getrecommendations! Published in 2018 at "Acta Neuropathologica"
DOI: 10.1007/s00401-018-1847-6
Abstract: Alzheimer’s disease (AD) is associated with a progressive loss of synapses and neurons. Studies in animal models indicate that morphological alterations of dendritic spines precede synapse loss, increasing the proportion of large and short (“stubby”)… read more here.
Keywords: compartmentalization; alzheimer disease; altered dendritic; evidence altered ... See more keywords
Influence of drought and season on compartmentalization of black locust (Robinia pseudoacacia L.) inoculated with Armillaria mellea
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Plant Pathology"
DOI: 10.1007/s10658-018-1444-5
Abstract: Effective compartmentalization of wounds in trees prevents the spreading of decay in wood. Climate extremes including drought can reduce the ability of trees to compartmentalize. In addition, compartmentalization of winter wounds is considered to be… read more here.
Keywords: compartmentalization; drought stressed; drought; locust robinia ... See more keywords
Physics of compartmentalization: How phase separation and signaling shape membrane and organelle identity
Sign Up to like & getrecommendations! Published in 2021 at "Computational and Structural Biotechnology Journal"
DOI: 10.1016/j.csbj.2021.05.029
Abstract: Compartmentalization of cellular functions is at the core of the physiology of eukaryotic cells. Recent evidences indicate that a universal organizing process – phase separation – supports the partitioning of biomolecules in distinct phases from… read more here.
Keywords: compartmentalization; phase separation; physics; separation ... See more keywords
Hif-1 stabilization in zebrafish neural crest
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2017.04.357
Abstract: One of the pivotal events in neurogenesis is compartmentalization where neural tissue is divided into domains and undergoes functional differentiation. A prominent example is cerebellar development which tructural and functional compartmentalization. Although the general anatomical… read more here.
Keywords: compartmentalization; hif stabilization; zebrafish neural; neural crest ... See more keywords
Biocatalysis in Polymersomes: Improving Multienzyme Cascades with Incompatible Reaction Steps by Compartmentalization
Sign Up to like & getrecommendations! Published in 2017 at "ACS Catalysis"
DOI: 10.1021/acscatal.7b00776
Abstract: Incompatibilities encountered in multienzyme syntheses often arise from inhibition or inactivation of individual enzymes by low-molecular-mass compounds. Polymersomes have the tremendous yet unproven potential to enhance the performance of cascade reactions by spatial separation of… read more here.
Keywords: compartmentalization; biocatalysis polymersomes; improving multienzyme; polymersomes improving ... See more keywords
Noncovalent Postmodification Guided Reversible Compartmentalization of Polymeric Micelles.
Sign Up to like & getrecommendations! Published in 2022 at "ACS macro letters"
DOI: 10.1021/acsmacrolett.2c00202
Abstract: Compartmentalized micelles (CMs) are promising tailor-made soft matters that mimic natural designed structures and functions. Despite the structure of complex CMs, manipulating CM structures accessibly and reversibly remains elusive. Here, we report the fabrication of… read more here.
Keywords: guided reversible; postmodification; compartmentalization; postmodification guided ... See more keywords
Functional compartmentalization in the hemocoel of insects
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-42504-3
Abstract: The insect circulatory system contains an open hemocoel, in which the mechanism of hemolymph flow control is ambiguous. As a continuous fluidic structure, this cavity should exhibit pressure changes that propagate quickly. Narrow-waisted insects create… read more here.
Keywords: insects; compartmentalization; functional compartmentalization; compartmentalization hemocoel ... See more keywords
A generalized kinetic model for compartmentalization of organometallic catalysis
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d1sc04983f
Abstract: Compartmentalization is an attractive approach to enhance catalytic activity by retaining reactive intermediates and mitigating deactivating pathways. Such a concept has been well explored in biochemical and more recently, organometallic catalysis to ensure high reaction… read more here.
Keywords: chemistry; organometallic catalysis; compartmentalization; kinetic model ... See more keywords