Persistent hepatocyte apoptosis promotes tumorigenesis from diethylnitrosamine-transformed hepatocytes through increased oxidative stress, independent of compensatory liver regeneration
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DOI: 10.1038/s41598-021-83082-7
Abstract: Hepatocellular carcinoma highly occurs in chronic hepatitis livers, where hepatocyte apoptosis is frequently detected. Apoptosis is a mechanism that eliminates mutated cells. Hepatocyte apoptosis induces compensatory liver regeneration, which is believed to contribute to tumor… read more here.
Keywords: apoptosis; liver regeneration; hepatocyte apoptosis; compensatory liver ... See more keywords