Compensatory mutations reducing the fitness cost of plasmid carriage occur in plant rhizosphere communities
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DOI: 10.1093/femsec/fiad027
Abstract: Plasmids drive bacterial evolutionary innovation by transferring ecologically important functions between lineages, but acquiring a plasmid often comes at a fitness cost to the host cell. Compensatory mutations, which ameliorate the cost of plasmid carriage,… read more here.
Keywords: fitness cost; plant rhizosphere; cost; compensatory mutations ... See more keywords
Plasmid Costs Explain Plasmid Maintenance, Irrespective of the Nature of Compensatory Mutations
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DOI: 10.3390/antibiotics12050841
Abstract: Conjugative plasmids often carry virulence and antibiotic-resistant genes. Therefore, understanding the behavior of these extra-chromosomal DNA elements gives insights into their spread. Bacteria frequently replicate slower after plasmids’ entry, an observation inconsistent with the plasmids’… read more here.
Keywords: plasmid costs; plasmid maintenance; compensatory mutations; costs explain ... See more keywords
Determination of potentially novel compensatory mutations in rpoc associated with rifampin resistance and rpob mutations in Mycobacterium tuberculosis Clinical isolates from peru
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DOI: 10.4103/ijmy.ijmy_27_20
Abstract: Background: Rifampicin (RIF) resistance in Mycobacterium tuberculosis is frequently caused by mutations in the rpoB gene. These mutations are associated with a fitness cost, which can be overcome by compensatory mutations in other genes, among… read more here.
Keywords: tuberculosis; resistance; compensatory mutations; tuberculosis clinical ... See more keywords