Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2
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DOI: 10.1038/s41467-019-11054-7
Abstract: Oct4, along with Sox2 and Klf4 (SK), can induce pluripotency but structurally similar factors like Oct6 cannot. To decode why Oct4 has this unique ability, we compare Oct4-binding, accessibility patterns and transcriptional waves with Oct6… read more here.
Keywords: pluripotency; oct4 sox2; chromatin opening; pluripotency reprogramming ... See more keywords