Articles with "competing endogenous" as a keyword



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Identification of miR‐145‐5p‐Centered Competing Endogenous RNA Network in Laryngeal Squamous Cell Carcinoma

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Published in 2019 at "PROTEOMICS"

DOI: 10.1002/pmic.201900020

Abstract: This study intends to investigate the transcriptional regulatory role of miR‐145‐5p in laryngeal squamous cell carcinoma (LSCC). LSCC cell line TU‐177 is transfected with miR‐145‐5p mimics, generating miR‐145‐5p‐overexpression LSCC cells. Whole transcriptome microarrays are used… read more here.

Keywords: cell; mir 145; cell carcinoma; squamous cell ... See more keywords
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Long non-coding RNA NEAT1 functions as a competing endogenous RNA to regulate S100A9 expression by sponging miR-196a-5p in rosacea.

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Published in 2021 at "Journal of dermatological science"

DOI: 10.1016/j.jdermsci.2021.02.005

Abstract: BACKGROUND Rosacea is a complex, chronic, and recurrent dermatologic condition that adversely affects quality of life and self-esteem. However, clinical relevance and molecular mechanisms underlying NEAT1 influence in rosacea remain unclear. OBJECTIVE The present study… read more here.

Keywords: s100a9 expression; rosacea; rna; mir 196a ... See more keywords
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Identification of a potentially novel LncRNA-miRNA-mRNA competing endogenous RNA network in pulmonary arterial hypertension via integrated bioinformatic analysis.

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Published in 2021 at "Life sciences"

DOI: 10.1016/j.lfs.2021.119455

Abstract: AIMS Pulmonary arterial hypertension (PAH) is a fatal cardiovascular disease with a cancer-like phenotype. Competing endogenous RNA (ceRNA) networks extensively involve in its pathological processes. But rare ceRNA networks and profound molecular mechanisms have been… read more here.

Keywords: network; arterial hypertension; analysis; endogenous rna ... See more keywords
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SP1-activated long noncoding RNA lncRNA GCMA functions as a competing endogenous RNA to promote tumor metastasis by sponging miR-124 and miR-34a in gastric cancer

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Published in 2020 at "Oncogene"

DOI: 10.1038/s41388-020-1330-4

Abstract: Long noncoding RNAs (lncRNAs) were demonstrated to play important roles in gene regulation and cancer progression. However, the functional roles of lncRNAs and the detailed mechanisms underlying gastric cancer (GC) progression remain largely unclear. Here,… read more here.

Keywords: long noncoding; gastric cancer; metastasis; cancer ... See more keywords
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Noncoding RNA-Associated Competing Endogenous RNA Networks in Doxorubicin-Induced Cardiotoxicity.

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Published in 2022 at "DNA and cell biology"

DOI: 10.1089/dna.2022.0022

Abstract: Accumulating evidence has indicated that noncoding RNAs (ncRNAs) are involved in doxorubicin-induced cardiotoxicity (DIC). However, the ncRNA-associated competing endogenous RNA (ceRNA)-mediated regulatory mechanisms in DIC remain unclear. In this study, we aimed to systematically investigate… read more here.

Keywords: induced cardiotoxicity; rna; competing endogenous; associated competing ... See more keywords
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A novel computational method for inferring competing endogenous interactions

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Published in 2017 at "Briefings in Bioinformatics"

DOI: 10.1093/bib/bbw084

Abstract: Posttranscriptional cross talk and communication between genes mediated by microRNA response element (MREs) yield large regulatory competing endogenous RNA (ceRNA) networks. Their inference may improve the understanding of pathologies and shed new light on biological… read more here.

Keywords: rna; computational method; novel computational; inferring competing ... See more keywords
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Genome-wide circular RNA profiling and competing endogenous RNA regulatory network analysis provide new insights into the molecular mechanisms underlying early somatic embryogenesis in Dimocarpus longan Lour.

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Published in 2022 at "Tree physiology"

DOI: 10.1093/treephys/tpac032

Abstract: Circular RNAs (circRNAs) are widely involved in plant growth and development. However, the function of circRNAs in plant somatic embryogenesis (SE) remains elusive. Here, by using high-throughput sequencing, a total of 5,029 circRNAs were identified… read more here.

Keywords: network; longan early; rna; somatic embryogenesis ... See more keywords
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Competing endogenous RNA network in newly diagnosed multiple myeloma by genetic microarray

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Published in 2020 at "Chinese Medical Journal"

DOI: 10.1097/cm9.0000000000001108

Abstract: Multiple myeloma (MM) is a blood malignancy characterized by the clonal proliferation of plasma cells, which increases the number of monoclonal immunoglobulins in blood and urine and causes target organ damage. Long non-coding RNAs (lncRNAs)… read more here.

Keywords: rna network; endogenous rna; multiple myeloma; competing endogenous ... See more keywords
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Systematic analysis competing endogenous RNA coexpression network as a potentially prediction prognostic biomarker for colon adenocarcinoma

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Published in 2022 at "Medicine"

DOI: 10.1097/md.0000000000030681

Abstract: Colon adenocarcinoma (COAD) is one of the most common types of colon cancer, represents a major public health issue due to its high incidence and mortality. Competing endogenous RNAs (ceRNAs) hypothesis has generated a great… read more here.

Keywords: network; prediction prognostic; prognostic biomarker; colon adenocarcinoma ... See more keywords
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Competing endogenous RNA network construction based on long non-coding RNAs, microRNAs, and mRNAs related to fat deposition in Songliao black swine.

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Published in 2023 at "Animal genetics"

DOI: 10.1111/age.13283

Abstract: China has a long history of pig breeding and a number of local breeds. The Songliao Black pig, bred in China in 2009, shows high variation in backfat thickness and therefore is well-suited to fat… read more here.

Keywords: rna; fat deposition; deposition; competing endogenous ... See more keywords
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Identification of circular RNAs as novel biomarkers and potentially functional competing endogenous RNA network for myelodysplastic syndrome patients

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Published in 2021 at "Cancer Science"

DOI: 10.1111/cas.14843

Abstract: Circular RNAs (circRNAs) have been identified to exert vital biological functions and can be used as new biomarkers in a number of tumors. However, little is known about the functions of circRNAs in myelodysplastic syndrome… read more here.

Keywords: circular rnas; myelodysplastic syndrome; hsa circrna; circrna ... See more keywords