Manipulating the complement system via Therapeutic plasmapheresis: Is there any therapeutic role?
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Apheresis"
DOI: 10.1002/jca.22001
Abstract: The complement system was discovered over a 100 years ago and now seems more sophisticated than originally thought. Complements have a role beyond innate immunity. Early complement components intervene on the rapid uptake of debris… read more here.
Keywords: system; role; complement system; plasma ... See more keywords
Complement component consumption in sepsis correlates better with hemostatic system parameters than with inflammatory biomarkers.
Sign Up to like & getrecommendations! Published in 2018 at "Thrombosis research"
DOI: 10.1016/j.thromres.2018.08.013
Abstract: INTRODUCTION The aim of this study was to investigate the role of C3 and C4 complement components in prediction of sepsis outcome. The secondary aim was to determine relationship between complement components and other inflammatory… read more here.
Keywords: sepsis; system; complement components; parameters inflammatory ... See more keywords
Relationships of Complement Components C3 and C4 and their Genetics to Cardiometabolic Risk in Healthy, Non-Hispanic White Adolescents
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric research"
DOI: 10.1038/s41390-019-0534-1
Abstract: Background Complement promotes inflammatory and immune responses and may affect cardiometabolic risk. This study was designed to investigate the effect of complement components C3 and C4 on cardiometabolic risk in healthy non-Hispanic white adolescents. Methods… read more here.
Keywords: risk healthy; risk; genetics; cardiometabolic risk ... See more keywords
Complement Components Are Expressed by Infiltrating Macrophages/Activated Microglia Early Following Viral Infection.
Sign Up to like & getrecommendations! Published in 2017 at "Viral immunology"
DOI: 10.1089/vim.2016.0175
Abstract: The individual innate immune components, interleukin-6 and complement component C3, play a role in the development of acute seizures in the Theiler's murine encephalomyelitis virus-induced seizure model. We examined the mRNA expression of various other… read more here.
Keywords: complement; macrophages activated; activated microglia; components expressed ... See more keywords
136. Increased Expression of Early Complement Components in Frontal Cortex in Schizophrenia
Sign Up to like & getrecommendations! Published in 2017 at "Schizophrenia Bulletin"
DOI: 10.1093/schbul/sbx021.194
Abstract: Background: The complement system is a key effector of innate immunity, mediating elimination of pathogens and debris via initiation of phagocytosis, inflammation, and cell lysis. Intriguingly, recent studies have identified an additional role for early… read more here.
Keywords: early complement; protein; schizophrenia; complement ... See more keywords
Associations Between Complement Components and Vitamin D and the Physical Activities of Daily Living Among a Longevous Population in Hainan, China
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.01543
Abstract: Background: Vitamin D and complement components shared some common pathophysiological pathways in the musculoskeletal system, circulation, and metabolism, which were linked to physical function. It is hypothesized that serum complement components may interact with vitamin… read more here.
Keywords: activities daily; serum complement; complement components; population ... See more keywords
CD44 Expression in Renal Tissue Is Associated with an Increase in Urinary Levels of Complement Components in Chronic Glomerulopathies
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24087190
Abstract: It is suggested that activated CD44+ cells play a profibrogenic role in the pathogenesis of active glomerulopathies. Complement activation is also involved in renal fibrogenesis. The aim of the study was to evaluate the role… read more here.
Keywords: cd44; complement components; cd44 expression; renal tissue ... See more keywords