LAUSR

Complement deposition induced by binding of anti-contactin-1 auto-antibodies is modified by immunoglobulins

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0 Published in 2017 at "Experimental Neurology"

DOI: 10.1016/j.expneurol.2016.10.006

Abstract: &NA; Inflammatory neuropathies associated with auto‐antibodies against paranodal proteins like contactin‐1 are reported to respond poorly to treatment with intravenous immunoglobulins (IVIG). A reason might be that IVIG interacts with the complement pathway and these… read more here.

Keywords: auto; complement deposition; auto antibodies; anti contactin ... See more keywords

3310Platelet complement C3 deposition predicts platelet hyperactivity in patients with type II diabetes

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0 Published in 2019 at "European Heart Journal"

DOI: 10.1093/eurheartj/ehz745.0074

Abstract: Atherothrombotic disease is associated with significant morbidity and mortality. Diabetes greatly increases the prothrombotic risk of individuals by factors that remain ill defined. Recently, increased plasma levels of complement C3 were associated with prothrombotic alterations… read more here.

Keywords: complement deposition; patients type; deposition; complement ... See more keywords

Multitransgenic Porcine Fibroblasts are Protected from Immunoglobulin Binding and Complement Deposition in a Xeno-Microfluidic Model

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0 Published in 2018 at "Transplantation"

DOI: 10.1097/01.tp.0000542707.45836.40

Abstract: Background One of the main issues that hamper xenotransplantation to be clinically feasible is humoral rejection. Xenoreactive antibodies, both natural or elicited, contribute significantly to rejection of xenotransplants by activation of complement and interactions with… read more here.

Keywords: complement deposition; bgr 4galnt2; immunoglobulin binding; complement ... See more keywords

Anti‐HIV‐1 antibodies trigger non‐lytic complement deposition on infected cells

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1 Published in 2019 at "EMBO reports"

DOI: 10.15252/embr.201949351

Abstract: The effect of anti‐HIV‐1 antibodies on complement activation at the surface of infected cells remains partly understood. Here, we show that a subset of anti‐Envelope (Env) broadly neutralizing antibodies (bNAbs), targeting the CD4 binding site… read more here.

Keywords: anti hiv; complement deposition; hiv antibodies; infected cells ... See more keywords