Articles with "complement evasion" as a keyword



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Complement Evasion by Lyme Disease Spirochetes.

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Published in 2020 at "Trends in microbiology"

DOI: 10.1016/j.tim.2020.05.004

Abstract: The complement system is an ancient arm of the innate immune system that plays important roles in pathogen recognition and elimination. Upon activation by microbes, complement opsonizes bacterial surfaces, recruits professional phagocytes, and causes bacteriolysis.… read more here.

Keywords: complement; disease spirochetes; complement evasion; lyme disease ... See more keywords
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IgM cleavage by Streptococcus suis reduces IgM bound to the bacterial surface and is a novel complement evasion mechanism

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Published in 2018 at "Virulence"

DOI: 10.1080/21505594.2018.1496778

Abstract: ABSTRACT Streptococcus suis (S. suis) causes meningitis, arthritis and endocarditis in piglets. The aim of this study was to characterize the IgM degrading enzyme of S. suis (IdeSsuis) and to investigate the role of IgM… read more here.

Keywords: igm cleavage; suis; complement evasion; cleavage ... See more keywords
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Streptococcus pneumoniae PspC Subgroup Prevalence in Invasive Disease and Differences in Contribution to Complement Evasion

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Published in 2018 at "Infection and Immunity"

DOI: 10.1128/iai.00010-18

Abstract: ABSTRACT The pneumococcal capsular serotype is an important determinant of complement resistance and invasive disease potential, but other virulence factors have also been found to contribute. Pneumococcal surface protein C (PspC), a highly variable virulence… read more here.

Keywords: pspc; subgroup; complement evasion; disease ... See more keywords
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Plasmodium falciparum Gametes and Sporozoites Hijack Plasmin and Factor H To Evade Host Complement Killing

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Published in 2023 at "Microbiology Spectrum"

DOI: 10.1128/spectrum.04493-22

Abstract: Current approaches to control malaria are complicated by the development of antimalarial-resistant parasites and insecticide-resistant vectors. Vaccines that block transmission to mosquitoes and humans are a plausible alternative to overcome these setbacks. ABSTRACT Plasmodium parasites… read more here.

Keywords: complement; gametes sporozoites; plasmin; complement evasion ... See more keywords
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Staphylococcal Complement Evasion Protein Sbi Stabilises C3d Dimers by Inducing an N-Terminal Helix Swap

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.892234

Abstract: Staphylococcus aureus is an opportunistic pathogen that is able to thwart an effective host immune response by producing a range of immune evasion molecules, including S. aureus binder of IgG (Sbi) which interacts directly with… read more here.

Keywords: evasion; complement; staphylococcal complement; helix swap ... See more keywords
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Complement Evasion Strategies of Viruses: An Overview

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Published in 2017 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2017.01117

Abstract: Being a major first line of immune defense, the complement system keeps a constant vigil against viruses. Its ability to recognize large panoply of viruses and virus-infected cells, and trigger the effector pathways, results in… read more here.

Keywords: complement evasion; viruses overview; strategies viruses; complement ... See more keywords