Inducing regulated necrosis and shifting macrophage polarization with anti‐EMMPRIN antibody (161‐pAb) and complement factors
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3a0520-333r
Abstract: Treatment of solid tumors is often hindered by an immunosuppressive tumor microenvironment (TME) that prevents effector immune cells from eradicating tumor cells and promotes tumor progression, angiogenesis, and metastasis. Therefore, targeting components of the TME… read more here.
Keywords: antibody 161; tumor cells; complement factors; death ... See more keywords
Complement factors and reticular pseudodrusen in intermediate age-related macular degeneration staged by multimodal imaging
Sign Up to like & getrecommendations! Published in 2020 at "BMJ Open Ophthalmology"
DOI: 10.1136/bmjophth-2019-000361
Abstract: Objective Systemic activation of the complement system in intermediate age-related macular degeneration (AMD) is understudied. Moreover, links between the presence of reticular pseudodrusen (RPD) and systemic complement dysregulation have not been studied. The aim of… read more here.
Keywords: complement factors; age related; related macular; intermediate age ... See more keywords
Associations between renal deposits of complement factors, disease activity and loss of renal function in lupus nephritis
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DOI: 10.1136/jclinpath-2021-207788
Abstract: Although deposits of complement factors in a kidney biopsy are typical of lupus nephritis, their prognostic relevance had never been investigated until a year ago. Then, around the same time, Kim and colleagues published a… read more here.
Keywords: lupus; disease; activity; pathway ... See more keywords
Prognostic significance of complement factors in severely ill patients with COVID-19
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DOI: 10.1136/jim-2021-002224
Abstract: Coagulopathy, cytokine release, platelet hyperactivity and endothelial activation are regarded as potential major contributors to COVID-19 morbidity. Complement activation might provide a bridge linking these factors in severe COVID-19 illness. In this study, we investigated… read more here.
Keywords: ill patients; complement factors; complement; prognostic significance ... See more keywords