Neisseria gonorrhoeae co-opts C4b-binding protein to enhance complement-independent survival from neutrophils
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Pathogens"
DOI: 10.1371/journal.ppat.1011055
Abstract: Neisseria gonorrhoeae (Gc) is a human-specific pathogen that causes the sexually transmitted infection gonorrhea. Gc survives in neutrophil-rich gonorrheal secretions, and recovered bacteria predominantly express phase-variable, surface-expressed opacity-associated (Opa) proteins (Opa+). However, expression of Opa… read more here.
Keywords: binding protein; neisseria gonorrhoeae; c4b binding; complement independent ... See more keywords
Insights Into the Pathogenesis of Bullous Pemphigoid: The Role of Complement-Independent Mechanisms
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.912876
Abstract: Bullous pemphigoid is an autoimmune blistering disease caused by autoantibodies targeting BP180 and BP230. While deposits of IgG and/or complement along the epidermal basement membrane are typically seen suggesting complement -mediated pathogenesis, several recent lines… read more here.
Keywords: bullous pemphigoid; complement; pemphigoid role; insights pathogenesis ... See more keywords
Dengue-Immune Humans Have Higher Levels of Complement-Independent Enhancing Antibody than Complement-Dependent Neutralizing Antibody.
Sign Up to like & getrecommendations! Published in 2017 at "Japanese journal of infectious diseases"
DOI: 10.7883/yoken.jjid.2016.379
Abstract: Dengue is the most important arboviral disease worldwide. We previously reported that most inhabitants of dengue-endemic countries who are naturally immune to the disease have infection-enhancing antibodies whose in vitro activity does not decrease in… read more here.
Keywords: complement dependent; antibody; complement independent; independent enhancing ... See more keywords